Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome
A Servais, V Frémeaux-Bacchi, M Lequintrec… - Journal of medical …, 2007 - jmg.bmj.com
Introduction: Abnormal control of the complement alternative pathway (CAP)(factor H, factor I
and membrane cofactor protein (MCP) deficiencies) is a well established risk factor for the
occurrence of haemolytic uraemic syndrome (HUS). In some instances, HUS may be
associated with an unusual glomerulonephritis with isolated C3 deposits
(glomerulonephritis C3). We determined whether HUS and glomerulonephritis C3 share
common genetic susceptibility factors. Methods: We identified 19 patients with …
and membrane cofactor protein (MCP) deficiencies) is a well established risk factor for the
occurrence of haemolytic uraemic syndrome (HUS). In some instances, HUS may be
associated with an unusual glomerulonephritis with isolated C3 deposits
(glomerulonephritis C3). We determined whether HUS and glomerulonephritis C3 share
common genetic susceptibility factors. Methods: We identified 19 patients with …
以上显示的是最相近的搜索结果。 查看全部搜索结果